Tasirin ƙwayoyin cuta na maganin iskar oxygen na hyperbaric a cikin raunin ƙonewa

Gabatarwa

Ana yawan samun raunukan ƙonewa a lokutan gaggawa kuma galibi suna zama hanyar shiga ga ƙwayoyin cuta. Fiye da raunukan ƙonewa 450,000 suna faruwa kowace shekara wanda ke haifar da mutuwar kusan mutane 3,400 a Amurka. Yawan raunukan ƙonewa a Indonesia shine 0.7% a cikin 2013. Fiye da rabin waɗannan A cewar bincike da yawa kan amfani da marasa lafiya an yi musu magani don kamuwa da ƙwayoyin cuta, wasu daga cikinsu suna da juriya ga wasu magungunan rigakafi. Amfani damaganin iskar oxygen na hyperbaric(HBOT) don magance ƙonewa yana da tasiri da dama, ciki har da sarrafa cututtukan ƙwayoyin cuta, da kuma hanzarta tsarin warkar da raunuka. Saboda haka, wannan binciken yana da nufin tabbatar da ingancin HBOT wajen hana haɓakar ƙwayoyin cuta.

Hanyoyi

Wannan wani bincike ne na gwaji a kan zomaye ta amfani da tsarin ƙungiyar kula da dabbobi bayan gwaji. An bai wa zomaye 38 ƙonewa na mataki na biyu a yankin kafada tare da farantin ƙarfe na ƙarfe wanda aka riga aka dumama shi na tsawon minti 3. An ɗauki ƙwayoyin cuta a ranakun 5 da 10 bayan an fallasa su ga ƙonewar. An raba samfuran zuwa ƙungiyoyi biyu, HBOT da iko. An gudanar da nazarin ƙididdiga ta amfani da hanyar Mann-Whitney U.

Sakamako

Kwayoyin cuta masu kama da na Gram sune suka fi yawa a cikin dukkan ƙungiyoyin biyu. Citrobacter freundi shine mafi yawan ƙwayoyin cuta masu kama da na Gram (34%) da aka samu a sakamakon al'adar ƙungiyoyin biyu.

Sabanin rukunin masu kula da cutar, babu wani ci gaban ƙwayoyin cuta da aka samu a sakamakon al'adar ƙungiyar HBOT, (0%) vs (58%). An lura da raguwar ci gaban ƙwayoyin cuta sosai a cikin ƙungiyar HBOT (69%) idan aka kwatanta da ƙungiyar masu kula da cutar (5%). Matakan ƙwayoyin cuta sun tsaya cak a cikin zomaye 6 (31%) a cikin ƙungiyar HBOT da zomaye 7 (37%) a cikin ƙungiyar masu kula da cutar. Gabaɗaya, akwai ƙarancin ci gaban ƙwayoyin cuta sosai a cikin ƙungiyar masu kula da cutar HBOT idan aka kwatanta da ƙungiyar masu kula da cutar (p < 0.001).

Kammalawa

Yin amfani da HBOT zai iya rage girman ƙwayoyin cuta a cikin raunukan ƙonewa.