Shanyewar jiki, wani mummunan yanayi wanda ke haifar da raguwar kwararar jini zuwa kyallen kwakwalwa kwatsam saboda cututtukan jini ko ischemic, shine babban abin da ke haifar da mutuwa a duk duniya kuma shine babban abin da ke haifar da nakasa. Manyan nau'ikan bugun jini guda biyu sune bugun jini na ischemic (wanda ya kai kashi 68%) da bugun jini na jini (32%). Duk da bambancin yanayin su a matakan farko, duka biyun suna haifar da raguwar wadatar jini da kuma cizon kwakwalwa a lokacin subacute da na yau da kullun.
Ciwon bugun jini na Ischemic
Ana nuna bugun jini na Ischemic (AIS) ta hanyar toshewar jijiyoyin jini kwatsam, wanda ke haifar da lalacewar ischemic ga yankin da abin ya shafa. A cikin matakin gaggawa, wannan yanayin hypoxic na farko yana haifar da tarin excitotoxicity, damuwa ta oxidative, da kunna microglia, wanda ke haifar da mutuwar jijiyoyi. A lokacin matakin subacute, sakin cytokines, chemokines, da matrix metalloproteinases (MMPs) na iya taimakawa wajen haifar da kumburin jijiyoyi. Abin lura shi ne, yawan matakan MMPs yana ƙara yawan iskar shaka ta katangar jini-kwakwalwa (BBB), yana ba da damar ƙaura ƙwayoyin leukocyte zuwa yankin da aka toshe, yana ƙara yawan aikin kumburi.
Maganin Yanzu Don Ciwon Zuciya Mai Tsanani
Manyan magungunan da suka fi tasiri ga AIS sun haɗa da thrombolysis da thrombocytopometry. Thrombolysis na iya amfanar marasa lafiya cikin awanni 4.5, inda magani da wuri ya zama mafi fa'ida. Idan aka kwatanta da thrombolysis, tiyatar thrombectomy ta injiniya tana da faffadan taga na magani. Bugu da ƙari, magungunan da ba na magani ba, waɗanda ba na cutarwa ba kamar sumaganin iskar oxygen, acupuncture, da kuma motsa jiki na lantarki suna samun karɓuwa a matsayin ƙarin jiyya ga hanyoyin gargajiya.
Tushen Maganin Oxygen na Hyperbaric (HBOT)
A matsin lamba na matakin teku (1 ATA = 101.3 kPa), iskar da muke shaka ta ƙunshi kusan kashi 21% na iskar oxygen. A ƙarƙashin yanayin jiki, rabon iskar oxygen da aka narkar a cikin plasma ba shi da yawa, kusan 0.29 mL (0.3%) ne kawai a cikin 100 mL na jini. A ƙarƙashin yanayin hyperbaric, shaƙar iskar oxygen 100% yana ƙara yawan iskar oxygen da aka narkar a cikin plasma sosai - har zuwa 3.26% a 1.5 ATA da 5.6% a 2.5 ATA. Saboda haka, HBOT yana da nufin haɓaka wannan ɓangaren iskar oxygen da aka narkar, yadda ya kamata.ƙara yawan iskar oxygen a cikin kyallen jiki a yankunan ischemic. A lokacin matsin lamba mai yawa, iskar oxygen tana yaɗuwa cikin kyallen hypoxic cikin sauƙi, tana kaiwa nisan yaɗuwa mai tsawo idan aka kwatanta da matsin lamba na yanayi na yau da kullun.
Zuwa yanzu, HBOT ta ga amfani sosai ga duka bugun jini na ischemic da kuma na jini. Bincike ya nuna cewa HBOT yana ba da tasirin kariya daga jijiyoyi ta hanyar hanyoyin kwayoyin halitta masu rikitarwa, na biochemical, da na hemodynamic, gami da:
1. Ƙara yawan iskar oxygen a cikin jijiyoyin jini, yana inganta isar da iskar oxygen zuwa kyallen kwakwalwa.
2. Daidaitawar BBB, rage kumburin kwakwalwa.
3. Inganta kwakwalwamicrocirculation, inganta metabolism na kwakwalwa da samar da makamashi yayin da ake kiyaye homeostasis na ion na tantanin halitta.
4. Daidaita kwararar jinin kwakwalwa don rage matsin lamba a cikin kwakwalwa da kuma rage kumburin kwakwalwa.
5. Rage kumburin jijiyoyi bayan bugun jini.
6. Rage apoptosis da necrosisbayan bugun jini.
7. Rage damuwa ta oxidative da kuma hana raunin sake yin aiki, wanda yake da mahimmanci a fannin cututtukan bugun jini.
8. Bincike ya nuna cewa HBOT na iya rage vasospasm bayan zubar jini na aneurysmal subarachnoid (SAH).
9. Shaida kuma tana goyon bayan fa'idar HBOT wajen haɓaka neurogenesis da angiogenesis.
Kammalawa
Maganin iskar oxygen mai ƙarfi yana gabatar da hanya mai kyau don magance bugun jini. Yayin da muke ci gaba da warware sarkakiyar murmurewa daga bugun jini, ƙarin bincike zai zama dole don inganta fahimtarmu game da lokaci, yawan magani, da hanyoyin HBOT.
A taƙaice, yayin da muke bincika fa'idodin maganin iskar oxygen mai ƙarfi don bugun jini, ya bayyana a fili cewa amfani da wannan maganin yana da yuwuwar kawo sauyi a yadda muke sarrafa bugun jini na ischemic, yana ba da bege ga waɗanda wannan yanayin da ke canza rayuwa ya shafa.
Idan kuna sha'awar bincika maganin iskar oxygen na hyperbaric a matsayin maganin da zai iya warkar da bugun jini, muna gayyatarku da ku ziyarci gidan yanar gizon mu don ƙarin koyo game da ɗakunan iskar oxygen na hyperbaric masu ci gaba. Tare da nau'ikan samfura iri-iri waɗanda aka tsara don amfanin gida da na ƙwararru, MACY-PAN yana ba da mafita waɗanda ke ba da ingantaccen maganin iskar oxygen don tallafawa lafiyar ku da tafiyar murmurewa.
Gano samfuranmu da kuma yadda zasu iya inganta lafiyar ku awww.hbotmacypan.com.
Lokacin Saƙo: Fabrairu-18-2025